BioActive-Tech Ltd (bioactivetech.pl) is a manufacturer of Hop-RXn extract – a natural reagent rich in xanthohumol (more than 96%).
BioActive-Tech Ltd developed the unique method of producing Hop-RXn (standard > 96%, but for special clients over 99% of xanthohumol).
We collaborate with Universities and Research Institutes.
BioActive-Tech Ltd produces Hop-RXn extract rich in xanthohumol (over 96% – UV-Vis spectroscopy, HPLC) from the common hop (Humulus Lupulus L.) by using a unique extraction method.
We can produce Hop-RXn at a large scale for highly demanding industries.
Hop-RXn is extracted from European, ecological hops which are planted in European countries.
Our scientists know almost everything about xanthohumol.
We have a unique method of producing Hop-RXn.
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“Hops (Humulus lupulus L.), a principal raw material of beer, have been widely used throughout the world in the brewing industry. It acts as a preservative and gives beer the unique aroma and flavor (McAdam et al., 2013; Dostalek et al., 2017). In addition, hops have been used as a medicinal plant for a long time throughout history owing to its richness in a variety of phenolic compounds (Zanoli and Zavatti, 2008). The dried hops contain 4–14% polyphenols, mainly phenolic acids, prenylated chalcones, flavonoids, catechins, and proanthocyanidins (Nikolic and van Breemen, 2013). Xanthohumol (Xn; 3′-[3,3-dimethylallyl]-2′,4′,4-trihydroxy-6′-methoxychalcone), the most abundant prenylated flavonoid with 0.1–1% of dry weight in hops, can be isolated from the female inflorescences. It is also a constituent of beer, a major dietary source of prenylated flavonoids, where it has been found at concentrations up to 0.96 mg/L (1.95 μM) (Chen et al., 2012).
The structure of Xn was firstly identified by Verzele et al. (1957). However, the beneficial pharmacological properties of Xn were not appreciated until 1990s, including antioxidant, anti-inflammatory, antibacterial, antiviral, antifungal, and antiplasmodial activity (Liu et al., 2015). In recent years, increasing evidences suggested the anticancer activity of Xn against NSCLC, leukemia, HCC, breast cancer, PCa, CCA, glioblastoma, pancreatic cancer, colon cancer, cervical cancer, melanoma, thyroid cancer, laryngeal squamous cell carcinoma (LSCC), and ovarian cancer.”
Adapted from the paper published online 2018 May 22. doi: 10.3389/fphar.2018.00530
For more information about xanthohumol: pubmed.ncbi.nlm.nih.gov
Order: minimum 1g or more
The Hop-RXn offer is directed only to Companies and Research Units
BioActive-Tech Sp. z o.o.
Al. W. Witosa 3
20-315 Lublin, Poland
KRS Nr 0000432070
Bank account number:
91 1020 3176 0000 5002 0178 6185